As of the 2018.g version of CYPETHERM programs with the EnergyPlus analysis engine, users can define more than one water-cooling and/or heating system in the same project, as long as other types of air conditioning systems are not defined. If other types of air conditioning systems are defined, as occurred in previous versions, only one type of water-air conditioning system can be defined of each of these types (cooling and heating) for all the building.
